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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: non GLP Screening test following OECD 202 principals

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium hydrogen oxalate
EC Number:
700-689-4
Cas Number:
41524-32-7
Molecular formula:
C17 H23 N O2 .C2 H2 O4
IUPAC Name:
6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium hydrogen oxalate
Details on test material:
- Name of test material (as cited in study report): trans-tilidin-oxalat, Erstabtrennung
- Physical state: solid
- Analytical purity: > 99.5 %
- Lot/batch No.: LV 8/10

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
TEST ORGANISM
- Common name: water flea
- Age at study initiation (mean and range, SD): 2 - < 24 h
- Feeding during test: no


Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Hardness:
according to OECD 202
Test temperature:
according to OECD 202
pH:
according to OECD 202
Dissolved oxygen:
according to OECD 202
Reference substance (positive control):
no

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
10 - 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

Applicant's summary and conclusion