Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The key studies were performed in compliance with GLP and to appropriate OECD, EU and EPA OPPTS guidelines with a sufficient level of detail to assess the quality of the studies. The studies were performed to a good standard in line with an accepted, standardised guidelines and were assigned a reliability score of 1 using the criteria for assessing data quality as set out in Klimisch (1997).
Short description of key information:
Key study:- Bowles (2011) 'CN-3384A: Reverse mutation assay "Ames test" using Salmonella typhimurium and Escherichia coli' conducted in line with OECD Guideline 471 and EU Method B.13/B.14 and EPA OPPTS 870.5265.
Key study:- Morris (2011) 'CN-3384A: Chromosome aberration test in human lymphocytes in vitro' conducted in line with OECD Guideline 473 and EU Method B.10 and EPA OPPTS 870.5375.
Key study:- Flanders (2011) 'CN-3384A: L5178Y TK +/- Mouse lymphoma assay' conducted in line with OECD Guideline 476 and EU Method B.17 and EPA OPPTS 870.5300.
The substance was considered to be non-mutagenic under the conditions of all three tests.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
The data do not indicate that any classification for genetic toxicity is required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
