Registration Dossier
Registration Dossier
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EC number: 413-060-1 | CAS number: 19186-97-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- other: ECHA inquiry result
- Title:
- Unnamed
- Year:
- 1 993
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Principles of method if other than guideline:
- A 72-hour static acute toxicity study of PB-370 was
conducted in green alga, Selenastrum capricornutum. Ten
replicate flasks, containing 100 ppm PB-370 dispersed by
ultrasonication, were inoculated with 8100 S.capricornutum
cells. Six replicate control flasks containing no PB-370
were inoculated with the same number of algal cells. Algal
cell concentrations were measured at 24, 48 and 72 hours.
The average specific growth rate and area under the growth
curve were computed from the count data. pH and temperature
were monitored at prescribed intervals. Analysis of PB-370
was conducted by a validated chromatographic method. - GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 413-060-1
- EC Name:
- -
- Cas Number:
- 19186-97-1
- Molecular formula:
- C15H24O4PBr9
- IUPAC Name:
- tris[3-bromo-2,2-bis(bromomethyl)propyl] phosphate
Constituent 1
Test organisms
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Study design
- Limit test:
- yes
- Total exposure duration:
- 72 h
Test conditions
- Hardness:
- <= 15 mg CaCO3/L
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.016 mg/L
- Basis for effect:
- biomass
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.016 mg/L
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 0.016 mg/L
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 0.016 mg/L
- Basis for effect:
- biomass
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
