Registration Dossier
Registration Dossier
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EC number: 249-060-1 | CAS number: 28510-23-8
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to fish
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
Study has been waived. Long-term fish toxicity study would not be considered appropriate as Daphnia Magna has been demonstrated to be the most sensitive species on the basis of the data that have already been conducted.
Key value for chemical safety assessment
Additional information
In the interest of animal welfare and following the principles of reducing the need to conduct animal testing, the long term fish toxicity test has been waived. It has been concluded that Daphnia Magna is the most sensitive species following the study reports obtained in the 21-d Daphnia reproduction study, acute Daphnia immobilisation, acute toxicity to fish, algal growth inhibition and ready biodegradation test. As such conducting a long term fish toxicity test would be futile as it is not likely to provide any significant additional data and would not be considered appropriate. Regulation (EC) No. 1907/2006 Article 25 (1) - Data sharing and avoidance of unnecessary testing.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
