Registration Dossier
Registration Dossier
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EC number: 231-679-3 | CAS number: 7681-82-5
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- April 18 to 20, 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD test gudeline with GLP principle
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Sodium lodide
- IUPAC Name:
- Sodium lodide
- Reference substance name:
- Sodium iodide
- EC Number:
- 231-679-3
- EC Name:
- Sodium iodide
- Cas Number:
- 7681-82-5
- Molecular formula:
- INa
- IUPAC Name:
- sodium iodide
- Test material form:
- solid: crystalline
- Details on test material:
- No data
Constituent 1
Constituent 2
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- 24h for range finding test and 24h for definitive test
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.27 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 1.19-1.38
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- In conclusion, the test substance is not classified to acute aquatic toxicity based on the test result and the unbiodegradable property as per EU CLP(Regulation (EC) No 1272/2008).
- Executive summary:
The test was performed to determine the acute toxicity of test substance to Daphnia magna during 48 hours according to OECD TG 202.0.04, 0.10, 0.26, 0.70, 1.88, 13.7, 37.00, 100.00, 270.00 mg/L of test substances were applied in the definitive test. EC50- 48h was determined to 1.27 mg/L and the 95% confidence limits was between 1.19 and 1.38 mg/L.
Thus, it shall be not classified to acute aquatic toxicity as per EU CLP (Regulation (EC) No 1272/2008).
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