Registration Dossier
Registration Dossier
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EC number: 926-191-9 | CAS number: 1181221-96-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
With high probability not harmful to aquatic algae.
No toxic effects occur at the range of the substances solubility.
EC50 (96h) > 1000 mg/L and NOEC (96h) >= 100 mg/L (nominal, WSF) for growth rate of Pseudokirchnerella subcapitata (OECD 201)
Key value for chemical safety assessment
Additional information
In a GLP guideline study following OECD 201 green algae (Pseudokirchnerella subcapitata) were exposed for 96 hours to
Hexamethylene diisocyanate, oligomers, reaction products withN-(3-trimethoxysilyl)propylbutylamine and Bis-(Trimethoxysilylpropyl)amine [BASF Coatings GmbH, 2013]. Based on the low water solubility of the test item the aquatic toxicity was determined by a water soluble fraction (WSF) with a limit loading rate of 1000 mg/L for the EC-value testing and with 100 mg/L for the NOEC-value testing. No algal growth inhibition was observed in the treatment compared to the control. Thus, the 96-h EC50 for growth rate inhibition is determined to be > 1000 mg/L and the NOEC for growth rate is >= 100 mg/L based on nominal loading concentrations.
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