Registration Dossier
Registration Dossier
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EC number: 926-191-9 | CAS number: 1181221-96-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish.
No toxic effects occur at the range of the substances solubility.
LC50 (96h) > 1000 mg/L (nominal, WSF) for Brachydanio rerio (OECD 203)
Key value for chemical safety assessment
Additional information
The acute aquatic toxicity of Hexamethylene diisocyanate, oligomers, reaction products with N-(3-trimethoxysilyl)propylbutylamine and Bis-(Trimethoxysilylpropyl)amine on fish was investigated in a GLP guideline study according to OECD 203 [BASF Coatings GmbH, 2013]. The static study used the zebrafish Danio rerio as test species. Based on the low water solubility of the test item a water soluble fraction (WSF) was prepared and the test was conducted as limit test with a nominal loading concentration of 1000 mg/L. After 96 hours of exposure no toxic effects on fish were observed.
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