Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute tests on all three trophic levels were performed with a water accommodated fraction to examine the aquatic toxicity of

Hexamethylene diisocyanate, oligomers, reaction products withN-(3-trimethoxysilyl)propylbutylamine and Bis-(Trimethoxysilylpropyl)amine. For all acute tests on fish, aquatic invertebrates and aquatic algae no toxic effects occurred at the range of the substances water solubility. Thus, the submission item is considered to be with high probability acutely not harmful to aquatic organisms.

No data on the long-term aquatic toxicity of Hexamethylene diisocyanate, oligomers, reaction products with N-(3-trimethoxysilyl)propylbutylamine and Bis-(Trimethoxysilylpropyl)amine are available. However, the absence of adverse effects in acute studies on all three trophic levels as well as the fate properties suggest a low potential for severe long-term toxicity of the submission item to the environment.