Registration Dossier
Registration Dossier
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EC number: 203-897-9 | CAS number: 111-70-6
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
No relevant toxicity studies are available. However, as sediment RCRs are lower than 1 and log Kow/log Koc < 3, no toxicity testing is proposed for this compartment.
The EPM strategy applied to sediment follows the rules set out in the integrated testing strategy (ITS) detailed in R.7.8.12, Chapter R.7b of the ECHA Guidance on information requirements and chemical safety assessment (v1.2, Nov. 2012, pp.138-139). No adequate toxicity study is available for the evaluation of the toxicity of heptanol to sediment organisms. Therefore, the freshwater and marine sediment PNECs were derived from their respective aquatic PNECs, using the EPM. The RCRs estimated with those PNECs are lower than 1 for both compartments and no further testing is therefore required to cover the risk for both sediment compartments. This information is presented in the CSA. It has to be noted that both n-octanol/water partition coefficient (log Kow) and adsorption coefficient (log Koc) are inferior to 3. Consequently, a chemical safety assessment for the sediment compartment was not mandatory, as stated in R.7.8.12.2, Chapter R.7b of the ECHA Guidance on information requirements and chemical safety assessment (v1.2, Nov. 2012, p.140): “The main property of a substance that triggers the assessment for the sediment compartment is the potential to adsorb or bind onto sediment. As trigger value for a sediment assessment, a log Kow of 3 is proposed”. The chemical safety assessment indicates an acceptable risk (all RCRs < 1) for both sediment compartments (both freshwater and marine).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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