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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Study period:
1976
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The study was performed before OECD test guidelines and GLP were established. The documentation is according to the best practice at the time the study was performed. However, some critical details of the test protocol and the results are not available.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
BASF test
GLP compliance:
no
Remarks:
Pre-GLP

Test material

Constituent 1
Chemical structure
Reference substance name:
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs.
EC Number:
284-932-5
EC Name:
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs.
Cas Number:
84989-41-3
Molecular formula:
C28.H52.O2 - C36.H68.O2
IUPAC Name:
(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one
Details on test material:
Test substance: other TS: Stearyldiketen TV 194/37

An AKD manufactured using a stearic acid rich blend of palmitic and stearic fatty acids.

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
olive oil
Doses:
no data
No. of animals per sex per dose:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 6 800 mg/kg bw

Any other information on results incl. tables

Clinical signs: Dyspnoe, Apathy, slow movement. Gross pathology: no signs of treatement.

Applicant's summary and conclusion

Conclusions:
Limited reporting interpretaion is not possible.