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EC number: 477-690-9 | CAS number: 874819-71-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
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- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2005-01-17 - 2005-07-13
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- yes
- Details on test solutions:
- Preparation of the test solution
The test solution was prepared in the following way:
- Weighing of 1000 mg test item
- Adding of dilution water up to a final volume of 1000 mL (stock solution)
- Filling with dilution water up to a final volume of 10 L
At the start of the test, the test item pool contained 10 L test solution with the test item at a nominal concentration of 100 mg/L dilution water. The control pool contained 10 L dilution water only.
The dilution water was prepared some days before the start of the test and stored without further aeration before use in the same cabinet and at the same temperatures as the fish test was performed. The pools were permanently aerated by an aeration pump. - Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Origin of the test organism:purchased from ZOO KNAPPIG, Sachsenpark, An der Passage 1, D-04356 Leipzig
Origin of the fish used in the test: holding and breeding in the testing facility under standardised laboratory conditions
Total length of the test fish: 2.4-3.0 cm - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Hardness:
- 2 mmol/L CaCO3, which corresponds to a hardness of 200 mg/l CaC03
- Test temperature:
- 21.7- 22.5 °C
- pH:
- 7.39 - 7.66
- Dissolved oxygen:
- 8.66 - 8.95 mg/l
- Nominal and measured concentrations:
- see below
- Reference substance (positive control):
- not required
- Key result
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- Cumulative mortality after 3, 6, 24, 48, 72 and 96 hours
Number of dead fish
Treatment group 3 h 6 h 24 h 48 h 72 h 96 h
Control (dilution water) 0 0 0 0 0 0
100 mgP 101/04/L 0 0 0 0 0 0 - Sublethal observations / clinical signs:
Treatment group
Analysed content of P 101/04 (mgP 101/04/L)
Oh
96 h
Control (dilution water)
0
0
100 mgP 101/04/L
100.9
100.2
Treatment group
Dissolved oxygen (mg/L)
Oh
24 h
48 h
72 h
96 h
Control (dilution water)
9.10
8.24
9.04
8.53
8.97
100 mg P 101/04/L
8.93
8.72
8.66
8.95
8.83
Treatment group
pH value
Oh
24 h
48 h
72 h
96 h
Control (dilution water)
7.44
7.32
7.59
7.24
7.06
lOOmgP 101/04/L
7.61
7.66
7.61
7.59
7.39
- Validity criteria fulfilled:
- yes
- Conclusions:
- Under the conditions of the described study no effects of P 101/04 on the mortality of fish were determined. The NOEC (no observed effect concentration) after 96 hours was 100 mg P 101/04 /L.
- Executive summary:
In a 96-h acute toxicity study, zebra fish (Danio rerio) were exposed to N- (2 -nitrophenyl) -phosphoric triamide at a nominal concentration of 100 mg/l under static conditions.
No effects of P101/04 on the mortality of fish were determined. The NOEC (no observed effect concentration) after 96 hours was 100 mg P 101/04 /L.
The validity criteria were accomplished:
Mortality at the end of the test: < 10 % in the control (observed: 0 %)
Test conditions: constant (observed: constant)
Oxygen concentration: > 60 % of the air saturation value throughout the test (observed: > 91 %)
Reference
Description of key information
OECD 203 guideline study, GLP: NOEC: 100 mg/l
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- EC50
- Effect concentration:
- 100 mg/L
Additional information
In a 96-h acute toxicity study according to OECD guideline 203, zebra fish (Danio rerio) were exposed to N- (2 -nitrophenyl) -phosphoric triamide at a nominal concentration of 100 mg/l under static conditions.
No effects of N-(2-Nitrophenyl)phosphoric triamide on the mortality of fish were determined. The NOEC (no observed effect concentration) after 96 hours was 100 mg P N-(2-Nitrophenyl)phosphoric triamid/L.
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