Registration Dossier
Registration Dossier
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EC number: 235-868-1 | CAS number: 13014-18-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Referenceopen allclose all
- Reference Type:
- other: ECOSAR calculation
- Title:
- Unnamed
- Reference Type:
- other: Estimation software
- Title:
- ECOlogical Structure-Activity Relationship Model (ECOSAR) Class Program v1.11
- Author:
- US EPA
- Year:
- 2 012
- Bibliographic source:
- United States Environmental Protection Agency, Washington DC, USA; March 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- ECOSAR v1.11: Estimation of acute and chronic toxicity to green algae
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,4-dichlorobenzoic acid
- EC Number:
- 200-067-8
- EC Name:
- 2,4-dichlorobenzoic acid
- Cas Number:
- 50-84-0
- Molecular formula:
- C7H4Cl2O2
- IUPAC Name:
- 2,4-dichlorobenzoic acid
- Reference substance name:
- C(=O)(O)c1c(Cl)cc(Cl)cc1
- IUPAC Name:
- C(=O)(O)c1c(Cl)cc(Cl)cc1
- Details on test material:
- - Name of test material : 2,4-Dichlorobenzoic acid
Constituent 1
Constituent 2
Test organisms
- Test organisms (species):
- other: green algae
Study design
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 179.36 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- act. ingr.
- Basis for effect:
- not specified
Applicant's summary and conclusion
- Conclusions:
- According to a sufficient reliable (Q)SAR estimation the EC50 value (96h) of green algea was estimated to be 179.36 mg/L.
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