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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-09-19 to 2011-09-26
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
ethyl 3-[(pyridin-2-yl)amino]propanoate
EC Number:
600-382-4
Cas Number:
103041-38-9
Molecular formula:
C10 H14 N2 O2
IUPAC Name:
ethyl 3-[(pyridin-2-yl)amino]propanoate

Results and discussion

Water solubility
Water solubility:
6.7 g/L
Conc. based on:
test mat.
Loading of aqueous phase:
20 mg/L
Incubation duration:
>= 48 - <= 96 h
Temp.:
20 °C
pH:
7.02
Remarks on result:
other: about 2 g of test item/ 100 mL of water analytical grade

Applicant's summary and conclusion

Conclusions:
From the experimental data obtained according to CIPAC methods MT 157, the guideline A.6 in Official Journal L 383 Part A and OECD Guideline No. 105, it can be concluded that the water solubility of BIBR 1048 Ester sample is 6.7 g/L at 20°C.