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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
The rationale to read-across the data is attached in Section 13.
Reason / purpose for cross-reference:
read-across source
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h
Nominal and measured concentrations:
Nominal loading rate: 100 mg/L
Key result
Duration:
96 h
Dose descriptor:
LL50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOELR
Effect conc.:
>= 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
No mortality was observed during the test, either in control or test groups.
No abnormal response of the fish was observed during the test period.
Validity criteria fulfilled:
yes
Conclusions:
In a limit test at nominal loading rate of 100 mg/L, yttrium oxide had no acute toxic effect on the fish Danio rerio.
This result is read across to yttrium oxide, europium-doped.
Executive summary:

The 96hr-acute toxicity of yttrium oxide to Brachydanio rerio was studied under static conditions according to OECD Guideline 203.

Fish were exposed to a control and the test chemical at nominal loading rate of 100 mg/L. Mortality/immobilization were observed daily. No mortality was observed during the test, neither in the control nor in the group exposed to the test item. The 96 hour LL50 and NOELR were thus > 100 mg/L and >= 100 mg/L, respectively.

This result is read across to yttrium oxide, europium-doped.

Description of key information

The 96-h LL50 obtained on the zebrafish (Brachydanio rerio) for yttrium oxide is > 100 mg/L based on nominal loading rate. Therefore, yttrium oxide is not harmful to fish up to its solubility limit into water.

Key value for chemical safety assessment

Additional information

The toxicity of the substance itself to fish was not tested, however, a study with the analogue yttrium oxide is available. The justification for read-across based on the analogue approach is described in a report (see section 13 of IUCLID)

The 96hr-acute toxicity of yttrium oxide to Brachydanio rerio was studied under static conditions according to OECD Guideline 203. Fish were exposed to control and test chemical at nominal loading rate of 100 mg/L. Mortality/immobilization were observed daily. No mortality was observed during the test, neither in the control nor in the group exposed to the test item. The 96 hour LL50 and NOELR were thus > 100 mg/L and >= 100 mg/L, respectively.