Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary source.

Data source

Reference
Reference Type:
secondary source
Title:
Occupational safety and health guidelines for chemical hazards, Supplement IV-OHG
Author:
National Technical Information Service (NTIS)
Year:
1995

Materials and methods

Type of sensitisation studied:
skin
Study type:
not specified
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No information.
GLP compliance:
no
Remarks:
(not applicable)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-dibutylaminoethanol
EC Number:
203-057-1
EC Name:
2-dibutylaminoethanol
Cas Number:
102-81-8
Molecular formula:
C10H23NO
IUPAC Name:
2-(dibutylamino)ethan-1-ol
Details on test material:
- Name of test material (as cited in study report): 2-n-Dibutylaminoethanol
No further data available.

Method

Type of population:
not specified
Ethical approval:
not specified
Subjects:
no data
Clinical history:
no data
Route of administration:
dermal

Results and discussion

Results of examinations:
Exposure to 2-n-dibutylaminoethanol causes irritation of the eyes, nose, throat, and skin in humans. By analogy with the effects caused by chemically similar compounds, exposure to 2-n-dibutylaminoethanol may also cause allergic reactions, such as asthma or rashes.

Applicant's summary and conclusion