Registration Dossier
Registration Dossier
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EC number: 470-080-3 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
1-((2-Butyloctyloxymethyl)-2-(3,4-dihydro-isoquinolinium-2-yl)ethyl)sulfate was tested in an activated sludge respiration inhibition test according to OECD guideline 209. The 180 minutes EC20 value was 960 mg/L to the oxygen consumption of activated sludge micro-organisms in the activated sludge respiration inhibition test. The EC50 was >1000 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 920 mg/L
Additional information
1-((2-Butyloctyloxymethyl)-2-(3,4-dihydro-isoquinolinium-2-yl)ethyl)sulfate was tested in an activated sludge respiration inhibition test according to OECD guideline 209. The nominal concentrations of the test item were 10, 100, 250, 500, 1000 mg/L. The incuabtion time was 180 minutes. The following effect concentrations (mg/L) were obtained based on nominal concentrations: The per cent inhibition (EC10; EC20; EC50 and EC80 ) were calculated by Probit analysis according to Finney. The values were given with a accuracy of 2 significant digits.
EC10 (180 min) = 920 mg/L nominal
EC20 (180 min) = 960 mg/L nominal
EC50 (180 min) > 1000 mg/L nominal
EC80 (180 min) >1000 mg/L nominal
In a supporting study, toxicity of 1-((2-Butyloctyloxymethyl)-2-(3,4-dihydro-isoquinolinium-2-y l)ethyl)sulfate on microorganisms was investigated by determing the effects on respiration rate for a period of 30 min in an activated sludge respiration inhibition test according to OECD guideline 209.
The EC20-, EC50- and EC80 -values (30 min) were > 1000 mg/ L.
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