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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04 July 2022 - 07 July 2022
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
GLP compliance:
yes (incl. QA statement)
Analytical monitoring:
yes
Details on sampling:
At the beginning, after 24 and 48 hours, and at the end of the test, the content of the test
item in the test solutions was determined
Vehicle:
no
Details on test solutions:
A stock solution containing 250.0 mg/L test item, corresponding to 100.5 mg/L active substance (a. s.), in algal medium (demineralised water enriched with minerals but without algae) was prepared.
Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Details on test organisms:
Genus Desmodesmus
Species subspicatus
SAG Strain Number 86.81
Taxonomic position Chlorophyta - Chlorophyceae
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h
Test temperature:
21.5 – 23.2 °C
pH:
7.4 - 7.8
Nominal and measured concentrations:
11.4 / 24.9 / 54.7 / 114.4 / 248.8 mg/L test item (respectively 4.6 / 10 / 22 / 46 / 100 mg/L active ingredient a. s.)
Reference substance (positive control):
yes
Remarks:
Potassium dichromate K2Cr2O7 (CAS No. 7778-50-9)
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
24.3 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
act. ingr.
Basis for effect:
growth rate
Key result
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
12.78 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
act. ingr.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
4.61 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
act. ingr.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
14.35 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
act. ingr.
Basis for effect:
yield
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
8.78 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
act. ingr.
Basis for effect:
yield
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
4.61 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
act. ingr.
Basis for effect:
yield
Results with reference substance (positive control):
72h ErC50 0.75 mg/L
72h EyC50 0.34 mg/L
Validity criteria fulfilled:
yes
Conclusions:
The growth rate inhibition of algae Desmodesmus subspicatus following exposure to the test chemical gave an 72 hr EC50 value of 24.3 mg a.i./L. The corresponding 72 hr EC10 was 12.78 mg a.i./L .

Description of key information

The growth rate inhibition of algae Desmodesmus subspicatus following exposure to the test chemical gave an 72 hr EC50 value of 24.3 mg a.i./L. The corresponding 72 hr EC10 was 12.78 mg a.i./L .

Key value for chemical safety assessment

EC50 for freshwater algae:
24.33 mg/L
EC10 or NOEC for freshwater algae:
12.78 mg/L

Additional information