Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
10 mg/kg sediment dw
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
1 mg/kg sediment dw
Assessment factor:
1 000
Extrapolation method:
assessment factor

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
insufficient hazard data available (further information necessary)

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
PNEC oral
PNEC value:
6.83 mg/kg food
Assessment factor:
300

Additional information

Conclusion on classification

Classification relevant information

Biodegradation:

- Not rapidly degradable: Ultimately biodegradable (67% degradation after 60 d, OECD 301F)

Bioaccumulation:

- BCF (11.5-251 L/kg ww) and BAF (1878 L/kg ww) (EPISuite™, BCFBAF v3.01)

- log Pow: > 9.3 (OECD 117)

Aquatic short-term toxicity

-   Fish: LC50 (96 h) > 100 mg/L (nominal, OECD 203)

-   Aq. invertebrates: EL50 (24 h) > 100 mg/L (nominal, OECD 202)

-   Algae: ErL50 (72 h) > 100 mg/L (nominal, OECD 201), > 0.078 mg/L (maximum water solubility)

Aquatic chronic toxicity

- Algae: NOEC (72 h) >= 100 mg/L (nominal, OECD 201), > 0.078 mg/L (maximum water solubility)

Classification according to CLP

Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate (AF-366) is not rapidly biodegradable in the environment. According to the above listed key toxicity data no acute aquatic toxicity could be observed at any of the three trophic levels (fish, algae, aquatic invertebrates). All effect concentrations were > 100 mg/L nominal test item concentration. No effects in the range of water solubility were recorded. Long-term data is available only for algae with a NOEC (72 h) >= 100 mg/L (nominal). As there is no chronic data available for all three trophic levels, the classification is based on chronic and acute data by considering the most stringent outcome as stated in the Guidance on the Application of the CLP Criteria (version July 2017). Based on the above given criteria, the substance is classified as Aquatic Chronic 4 (H413), according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).