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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From January 24 to March 22, 2022
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
conducted under GLP conditions
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
yes
Remarks:
Rate of change extrapolated from the linear regression of the range 323.15K and 573.15K - see Any other information on materials and methods incl. tables section for more details
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
yes
Remarks:
Rate of change extrapolated from the linear regression of the range 323.15K and 573.15K - see Any other information on materials and methods incl. tables section for more details
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Deviations:
yes
Remarks:
Rate of change extrapolated from the linear regression of the range 323.15K and 573.15K - see Any other information on materials and methods incl. tables section for more details
GLP compliance:
yes (incl. QA statement)
Type of method:
method according to Siwoloboff
Boiling pt.:
645 K
Atm. press.:
101 325 Pa
Key result
Boiling pt.:
372 °C
Atm. press.:
101 325 Pa

Accuracy checking:
The accuracy of the instrument was checked by determining the melting point of a certified sample of benzoic acid (certified melting point: 121.8°C - 123.0°C ±0.3°C).
The results were:
First determination: 121.6°C -123.4°C
Second determination: 121.6°C-123.0°C
Third determination: 121.7°C -123.0°C


Boiling point determination:
First determination: observed boiling point: 370.5°C
Second determination: observed boiling point: 370.9°C
During the experiment the substance became yellow around 350°C


 


Correction to normalized pressure:


The atmospheric pressure at the time of the experiment was 98.35 kPa (Meteo Suisse).
A correction of the temperature to normalised pressure (101.325 kPa) was made.


The determination of this correction factor was made using the Sidney Young equation, as recommended in OECD guideline 103:


Tn= T + (fT·Δp) 


 


Where:          Δp = 101.325 kPa – p


         p = pressure in kPa; the pressure was obtained from the Swiss meteorological service for the time of the experiment;


f= rate of change of boiling temperature with pressure in K/kPa, here a value of 0.53 K/kPa, (linear interpolation of the values for 323.15 K and 573.15 K as published in the OECD guideline 103) was used.


                      T = temperature in K


                      Tn= normal boiling point


 


After correction, it can be concluded that the standard boiling point of the test item is (values rounded off): 645K (372°C).

Conclusions:
From the tests described above, it can be estimated that the standard boiling point of the test item is (values rounded off):
645 K (372°C)
Executive summary:

The boiling point of the test item was measured according to OECD Guideline No. 103 (principle according to Siwoloboff).


The result can be expressed as follows (values rounded off):
The boiling point of the test item is 645 K (372°C).

Description of key information

The boiling point of the test item was measured according to OECD Guideline No. 103 (principle according to Siwoloboff).


The result can be expressed as follows (values rounded off):
The boiling point of the test item is 645 K (372°C).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
372 °C

Additional information