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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

logPow > 6.2 at 22 °C (experimental)
logPow = 8.4 (QSAR)

Key value for chemical safety assessment

Log Kow (Log Pow):

Additional information

The octanol-water partition coefficient, log Pow, of the substance 2 -Hexyl-2 '-hydroxy-5 'methyldecananilide (AF-654), was investigated using an HPLC method according to OECD Guideline 117 and EU Method A.8. Since the substance appeared outside the validity range, only the lower limit of 6.2 could be derived. In order to obtain a value for the chemical safety assessment, the Rekker calculation method was applied, resulting in the log Pow value of 8.4. The two estimations are consistent.