Registration Dossier
Registration Dossier
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EC number: 700-485-5 | CAS number: 939402-02-5
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
DVS005u was determined to be not readily biodegradable according to a study performed in line with GLP and to the standardised guidelines OECD 301 and EU Method C.4-C. The substance was determined to be not inherently biodegradable in an OECD 302C Inherent Biodegradability: Modified MITI Test (II).
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The key study (Clarke, 2010) was conducted in line with GLP and standardised guidelines with a sufficient level of detail to assess the quality of the study. The ready biodegradability study measured CO2 evolution in activated sludge under aerobic conditions. 20 % degradation was observed over 28 days and so the test material was considered to be not readily biodegradable.
Makido (2011) has been provided as a supporting study. The study was conducted in line with GLP and standardised guidelines with a sufficient level of detail to assess the quality of the study. The BOD was calculated to be 0%, showing that biodegradation did not occur. The transformation products were measured at the end of the study and it was determined that 82% to the test material had hydrolysed, where the mass balance of the transformation products and the residual rate was 99-100%. The test material was again considered not to be readily biodegradable.
Mei (2014) has also been provided as a supporting study. In the OECD 302C Inherent Biodegradability: Modified MITI Test (II) the percentage biodegradation at the end of the test by BOD were 0%. At the end of the test, the abiotic degradation rate of the test substance was 91.7%, so it's of little importance to calculate the primary biodegradation according to the residual content of test substance.
All 3 studies were performed to a good standard and have been assigned a reliability score of 1 using the principles for assessing data quality as set out in Klimisch (1997).
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