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Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 08 July 2014 to 22 October 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
31.3 g/L
Conc. based on:
test mat.
Remarks:
± 0.4 g/L.
Temp.:
20 °C
pH:
>= 5.7 - <= 6.3

Measurements of Water Solubility at 20˚C:






































Sample number



Time (days)



Concentration (g/L)



Mean concentration (g/L)



pH



1A, 1B



1



31.6, 31.7



31.6



6.2, 6.3



2A, 2B



2



31.2, 31.5



31.3



5.8, 5.8



3A, 3B



3



31.4, 30.7



31.0



5.8, 5.7



Water solubility (mean of all samples)



31.3 ± 0.4 g/L



 

Conclusions:
The water solubility of 2,2-Difluoroethyl acetate was found to be equal to 31.3 ± 0.4 g/L at 20°C.
Executive summary:

The water solubility of 2,2-Difluoroethyl acetate was investigated in a GLP-compliant study according to OECD test guideline 105 using the shake flask method. The water solubility was determined to be equal to 31.3 ± 0.4 g/L. at 20°C.

Description of key information

The water solubility of 2,2-Difluoroethyl acetate is equal to 31.3 ± 0.4 g/L at 20°C.

Key value for chemical safety assessment

Water solubility:
31.3 g/L
at the temperature of:
20 °C

Additional information

An experimental study performed under GLP compliance and in accordance with OECD test guideline 105 was flagged as a key study and assigned a Klimisch score of 1. It reports that 2,2-Difluoroethyl acetate has a water solubility of 31.3 ± 0.4 g/L at 20°C.