Registration Dossier
Registration Dossier
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EC number: 446-560-3 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 Apr - 30 Apr 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- Test method A.6 for determination of watersolubility, EG-guideline 92/69.
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 5.6 g/L
- Temp.:
- 20 °C
- pH:
- 5
- Details on results:
- The key value is the mean of three measured concentrations.
- Conclusions:
- The water solubility of the test substance in the preliminary test was determined to be: 5.6 g/L.
- Executive summary:
The water solubility of the test substance in the preliminary test was determined to be: 5.6 g/L.
Reference
Test temperature: 20°C
pH value:
flask 1: 5.0
flask 2: 4.6
flask 3: 4.3
concentration:
flask 1: 5.6 g/L
flask 2: 5.6 g/L
flask 3: 5.7 g/L
mean value: 5.6 g/L
Validity criteria for the measurement of the water solubility:
| Target condition according to guideline 92/69/EWG A.6: | Actual condition according to the study: | Validity criteria met: |
| The test is preferably run at 20 ± 0.5 °C. | The test was performed at 20 °C. | Yes |
| A substance-specific analytical method is preferred for these determinations, since small amounts of soluble impurities can cause large errors in the measured solubility. Examples of such methods are: gas or liquid chromatography, titration methods, photometric methods, voltametric methods. | HPLC was used for analytical measurements. | Yes |
| The pH of each sample should be recorded. | The pH of each sample is reported. | Yes |
Description of key information
The water solubility of the test substance in the preliminary test was determined to be: 5.6 g/L.
Key value for chemical safety assessment
- Water solubility:
- 5.6 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
