Registration Dossier
Registration Dossier
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EC number: 686-994-2 | CAS number: 54621-18-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
In silico mutagenicity prediction:
With regard to the prediction models used (Leadscope, DEREK, VITIC) the substance raised no structural alert for mutagenicity (negative prediction) [Result, July 2021].
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
- Derek Version: Derek Nexus: 6.1.0, Nexus: 2.3.0,Derek KB 2020 1.0
- Leadscope Version: 3.0.2-4
- VITIC Version: 2.6.1
No testing data are available for the substance.
In silico assessments on the mutagenic potential using (Q)SAR methologies were performed with the following tools:
Results:
Negative prediction in DEREK.
Leadscope does not detect any known alerting substructure.
The absence of bacterial mutagenicity alerts in Leadscope together with the negative call in DEREK is sufficient for a negative mutagenicity prediction.
In summary, no mutagenic potential is concluded for the substance.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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