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Dissociation constant

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dissociation constant
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance has no ionic structure

Description of key information

According to "Guidance on Information Requirements and Chemical Safety Assessment. Chapter R.7a: Endpoint specific guidance, Version 6.0 (July 2017)", "it is important to note that the dissolution of salts from their crystal lattice into individual ions is not intended to be covered by the endpoint dissociation constant. Therefore this section refers only to acid dissociation (pKa)". No acid dissociation is expected for the test item.

Key value for chemical safety assessment

Additional information