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EC number: 204-442-7 | CAS number: 121-00-6
Endpoint summary
Administrative data
Description of key information
Bioaccumulation:aquatic /sediment:
The bioconcentration factor (BCF) for test chemical was determined according static fish test. The BCF value was observed to be 16-21 L/kg at dose concentration 0.0001 mg/L and 8.1-18 L/kg at dose concentration 0.00001 mg/L on test organism Cyprinus carpio during 6 weeks period. Therefore it is concluded that this test chemical is nonbioaccumulative.
Additional information
Bioaccumulation:aquatic /sediment:
Various experimental studies and one prediction study have been conducted to determine bioaccumulation concentartion factor (BCF) of test chemical and their results are summarized below
In first study the Bioaccumulation test was conducted for 6 weeks for determination the bioconcentration factor (BCF) of test chemical on test organism Cyprinus carpio.
Recovery ratio : Test water : 1st concentration area : 90.1 %, 2nd concentration area : 79.6 %, Fish : 92.7 %, - Limit of detection : Fish : 0.
ppm And Nominal concentrations used in the study as - 1st Concentration area: 0.0001 mg/L, 2nd Concentration area : 0.00001 mg/L and Range finding study was carried out on Rice fish (Oryzias latipes) TLm(48h) 6.4 ppm(w/v), Rice fish (Oryzias latipes).
Thus according to static Fish test the bioconcentration factor (BCF) for test chemical was determined according static fish test. The BCF value was observed to be 16-21 L/kg at dose concentration 0.0001 mg/L and 8.1-18 L/kg at dose concentration 0.00001 mg/L on test organism Cyprinus carpio during 6 weeks period.
Therefore it is concluded that this test chemical is nonbioaccumulative.
Next study was also reviewed from authoritative database in this the BCF value of test chemical was estimated is 57 dimensionless by using log Kow of 3.50 and regression derived equation and it is far less than 2000 so it is concluded that this chemical is non bioaccumulative.
Last study was the prediction done from EPI suite (2018) in this the estimated bioconcentration factor (BCF) for test chemical iwas estimated to be 57.07L/kg wet-wt. This value does not exceed the bioconcentration threshold of 2000. Thus it is concluded that test chemical is not expected to bioaccumulate in the food chain.
On the basis of all the studies mentioned above it is concluded that the BCF value of test chemical is in range of 8.1 to 57 dimensionless. By considering this range BCF value it is concluded that test chemical is non- bioaccumulative in aquatic species.
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