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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
ca. 1.4
Temp.:
20 °C
pH:
ca. 6
Conclusions:
The partition coefficient (n-octanol/water) of the test item was estimated on the ration of the individual solubilities of the test item in water and n-octanol. The solubilities were determined according to the flask method. The partition coefficient Pow of the test item was estimated to:
logPow (loading rate 10g/l) < 0.6
log Pow (loading rate 1 g/l) < 1.4
Executive summary:

The partition coefficient (n-octanol/water) of the test item was estimated on the ration of the individual solubilities of the test item in water and n-octanol. The solubilities were determined according to the flask method. The partition coefficient Pow of the test item was estimated to:
logPow (loading rate 10g/l) < 0.6
log Pow (loading rate 1 g/l) < 1.4

Description of key information

The partition coefficient (n-octanol/water) of the test item was estimated on the ration of the individual solubilities of the test item in water and n-octanol. The solubilities were determined according to the flask method. The partition coefficient Pow of the test item was estimated to:
logPow (loading rate 10g/l) < 0.6
log Pow (loading rate 1 g/l) < 1.4

Key value for chemical safety assessment

Log Kow (Log Pow):
1.4
at the temperature of:
20 °C

Additional information