Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- GLP compliance:
- yes (incl. QA statement)
- Dissociating properties:
- not determined
- Remarks on result:
- not determinable because of methodological limitations
- Conclusions:
- The dissociation constant of the test item should be determined according to the European Commission Regulation (EC) No. 2017/735, A.25 and according to the OECD test guideline 112. Despite adding water miscible organic solvents the solubility of the test item was too low for the determination of dissociation constants.
- Executive summary:
The dissociation constant of the test item should be determined according to the European Commission Regulation (EC) No. 2017/735, A.25 and according to the OECD test guideline 112. Despite adding water miscible organic solvents the solubility of the test item was too low for the determination of dissociation constants.
Reference
Description of key information
The dissociation constant of the test item should be determined according to the European Commission Regulation (EC) No. 2017/735, A.25 and according to the OECD test guideline 112. Despite adding water miscible organic solvents the solubility of the test item was too low for the determination of dissociation constants.
Key value for chemical safety assessment
Additional information
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