Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Non mutagenic

Additional information

Some alert for mutagenicity and carcinogenicity was found for the target substance, associated to the nitroaromatic structure and quinones. Mutagenic and carcinogenic activity was also found for some of the analogue substances.

Even though some concern arises also for the target substance, due to the lack of information on the substance itself and on analogue substances showing a higher structural similarity, a classification as mutagen and carcinogen is considered too conservative. Nevertheless, these alerts are seriously taken into account and even if the substance is already used under strictly controlled conditions, a special attention is paid for human exposure and for the environment.

Further information are available in the attachment in IUCLID section 13.2.

Justification for classification or non-classification

Available information on target substance and structural analogues indicate some concern. However, a classification as mutagen is considered too conservative. A classification within the CLP Regulation (EC 1272/2008) is not proposed.