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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR
Principles of method if other than guideline:
QSAR
GLP compliance:
no
Key result
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
ca. 491 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Validity criteria fulfilled:
not specified
Conclusions:
Prediction Acute EC50 (algae) equal to 491 mg/L, based on Esters model.
ECOSAR assigned the target chemical 2,4,8,10-Tetraoxa-3,9-dithiaspiro[5.5]undecane,
3,3,9,9-tetraoxide to the class of Excess Toxicity “Esters”.
ECOSAR includes a variety of structures identified in the Esters class, including Sulfuric
Acid or Sulfonate Esters. Sulfonate and sulfuric acid esters are identified by the following
structures:
Executive summary:

Prediction Acute EC50 (algae) equal to 491 mg/L, based on Esters model.

Description of key information

Moderate reliable QSAR

Key value for chemical safety assessment

EC50 for freshwater algae:
491 mg/L

Additional information