1H-Pyrazole-4-carbonyl chloride, 3-(difluoromethyl)-1-methyl-

Guidance on Safe Use

First-aid measures

- After inhalation:

Move to fresh air. Keep patient warm and at rest. Oxygen or artificial respiration if needed. Call a physician or poison control center immediately.

- After skin contact:

Wash off thoroughly with plenty of soap and water, if available with polyethyleneglycol 400, subsequently rinse with water. Call a physician or poison control center immediately.

- After eye contact:

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a physician or poison control center immediately.

- After swallowing

Rinse mouth. Do NOT induce vomiting. Risk of product entering the lungs on vomiting after ingestion. Call a physician or poison control center immediately.

Fire-fighting measures

- Suitable extinguishing agents:

Water spray, Carbon dioxide (CO2), Foam, Sand

- Special hazards caused by the material, its products of combustion or resulting gases:

In the event of fire the following can be released:

Carbon monoxide (CO), Hydrogen chloride (HCl), Hydrogen cyanide (hydrocyanic acid), Sulphur oxides, Nitrogen oxides (NOx)

- Protective equipment:

In the event of fire and/or explosion do not breathe fumes.

In the event of fire, wear self-contained breathing apparatus

- Additional information:

Contain the spread of the fire-fighting media.

Do not allow run-off from fire fighting to enter drains or water courses

Accidental release measures

- Person-related safety precautions:

Avoid contact with spilled product or contaminated surfaces.

Remove all sources of ignition. Use personal protective equipment.

- Measures for environmental protection:

Do not allow to get into surface water, drains and ground water.

- Measures for cleaning/collecting:

Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Clean contaminated floors and objects thoroughly, observing environmental regulations. Keep in suitable, closed containers for disposal.

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

Advice on safe handling

Use only in area provided with appropriate exhaust ventilation.

Advice on protection against fire and explosion

Vapours may form explosive mixture with air. Keep away from heat and sources of ignition. Take measures to prevent the build up of electrostatic charge. Vapours are heavier than air and may spread along floors.

Hygiene measures

Avoid contact with skin, eyes and clothing. Keep working clothes separately. Wash hands immediately after work, if necessary take a shower. Remove soiled clothing immediately and clean thoroughly before using again. Garments that cannot be cleaned must be destroyed (burnt).

Requirements for storage areas and containers

Store in original container. Keep containers tightly closed in a dry, cool and well-ventilated place. Store in a place accessible by authorized persons only. Protect against moisture. Keep away from direct sunlight.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

no transport intended

Shipping

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

no transport intended

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

no transport intended

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

no transport intended

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

Respiratory protection

If product is handled while not enclosed, and if contact may occur:

Wear respirator with an organic vapours and gas filter mask (protection factor 10) conforming to EN140 type A or equivalent.

Respiratory protection should only be used to control residual risk of short duration activities, when all reasonably practicable steps have been taken to reduce exposure at source e.g. containment and/or local extract ventilation. Always follow respirator manufacturer's instructions regarding wearing and maintenance.

Hand protection

Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time.

Wash gloves when contaminated. Dispose of when contaminated inside, when perforated or when contamination on the outside cannot be removed. Wash hands frequently and always before eating, drinking, smoking or using the toilet.

Material Nitrile rubber, Rate of permeability > 480 min, Glove thickness > 0,4 mm, Protective index Class 6

Directive Protective gloves complying with EN 374.

Eye protection

Wear goggles (conforming to EN166, Field of Use = 5 or equivalent) and faceshield (conforming to EN166, Field of Use = 3 or equivalent).

Skin and body protection

Wear standard coveralls and Category 3 Type 4 suit.

If there is a risk of significant exposure, consider a higher protective type suit.

Wear two layers of clothing wherever possible. Polyester/cotton or cotton overalls should be worn under chemical protection suit and should be professionally laundered frequently. If chemical protection suit is splashed, sprayed or significantly contaminated, decontaminate as far as possible, then carefully remove and dispose of as advised by manufacturer.

General protective measures

If product is handled while not enclosed, and if contact may occur: Complete suit protecting against chemicals

Stability and reactivity

- Hazardous Reactions

No hazardous reactions when stored and handled according to prescribed instructions.  

Reacts with water under formation of hazardous gases.

Disposal considerations

During the whole life cycle of the substance all necessary measures in accordance to art. 18(4) of (EC) 1907/2006 are undertaken. The substance is handled under strictly controlled conditions.

Dispose in accordance with current regulations and, if necessary, after consultation with the site operator and/or with the responsible authority, the product may be taken to a waste disposal site or incineration plant.

Waste air from the process is being burnt.

Solvents are recycled or burned.

Mother liquors and organic waste is being burnt.

Aqueous waste is transferred to the sites WWTP or burnt.