Registration Dossier
Registration Dossier
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EC number: 222-468-7 | CAS number: 3483-12-3
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 January 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Version / remarks:
- 2012
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Version / remarks:
- Regulation EC No. 440/2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: EPA OCSPP Test Guideline 830.7300. Density/Relative Density/Bulk Density
- Version / remarks:
- 2002
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: gas comparison pycnometer
Test material
- Reference substance name:
- (R*,R*)-1,4-dimercaptobutane-2,3-diol
- EC Number:
- 222-468-7
- EC Name:
- (R*,R*)-1,4-dimercaptobutane-2,3-diol
- Cas Number:
- 3483-12-3
- Molecular formula:
- C4H10O2S2
- IUPAC Name:
- 1,4-disulfanylbutane-2,3-diol
Constituent 1
- Specific details on test material used for the study:
- Batch No.: 44606300 / 50774
Storage Conditions: 2°C to 8°C, under nitrogen
Results and discussion
Densityopen allclose all
- Key result
- Type:
- relative density
- Density:
- 1.377 other: dimensionless
- Temp.:
- 20 °C
- Remarks on result:
- other: The relative density is calculated by dividing the density of the test item by the density of water at 4 °C.
- Type:
- density
- Density:
- 1.377 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: the density of the test item is given as the mean value of two measurements.
Any other information on results incl. tables
The individual density measurements were 1.37770 g/cm3 (test 1) and 1.37653 g/cm3 (test 2).
Applicant's summary and conclusion
- Conclusions:
- According to OECD Test Guidelines 109 (2012), Regulation EC No. 440/2008 Method A.3. and EPA OCSPP Test Guideline 830.7300 (2002), the relative density of the test item 1,4 Dithiothreitol (CAS no. 3483-12-3) at 20°C ± 0.01 °C (compared to water at 4°C) was determined to be 1.377.
- Executive summary:
According to OECD Test Guidelines 109 (2012), Regulation EC No. 440/2008 Method A.3. and EPA OCSPP Test Guideline 830.7300 (2002), the relative density of the test item 1,4 Dithiothreitol (CAS no. 3483-12-3) at 20°C ± 0.01 °C (compared to water at 4°C) was determined to be 1.377.
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