Reaction mass of tetrasodium 5-{[4-chloro-6-(4-{[2-(sulfonatooxy)ethyl]sulfonyl}anilino)-1,3,5-triazin-2-yl]amino}-4-hydroxy-3-[(4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl) diazenyl]naphthalene-2,7-disulfonate and trisodium 5-({4-chloro-6-[4-(vinylsulfonyl) anilino]-1,3,5-triazin-2-yl}amino)-4-hydroxy-3-[(4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)diazenyl]naphthalene-2,7-disulfonate

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: Guidance Document JRC, ECB/TM/February 1996

GLP compliance:

yes (incl. QA statement)

Type of distribution:

volumetric distribution

Percentile:

D50

Mean:

ca. 500 µm

Width of	1st sieving		2nd sieving			STD
mesh	net weight	weight	net weight	weight	mean	dev
[μm]	[g]	[%]	[g]	[%]	[%]	[%]
2000	0	0	0	0	0	0
1000	6.63	13.14	4.10	8.07	10.61	3.58
500	24.08	47.71	27.95	55.04	51.38	5.18
250	15.91	31.52	14.42	28.40	29.96	2.21
125	3.36	6.66	4.12	8.11	7.39	1.03
75	0.56	1.11	0.28	0.55	0.83	0.39
< 75	0.04	0.08	0	0	0.02	0.08

Conclusions:

Only 0.02 % (w/w) of the test item were below 75 μm. The approximate mean particle size was 500 µm.

Executive summary:

The test material is a clumpy powder. By visual observation, the particle size of the test item was too big to determine the distribution by laser diffraction method. Based on the visual observation, the sieve method was selected. Only 0.02 % (w/w) of the test item were below 75 μm.

Reference 2

Endpoint:

particle size distribution (granulometry)

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is marketed or used in a non solid or granular form

Percentile:

D50

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

Description of key information

The particle size is not a function of the chemical but a function of the spray dryer or dedusting technique used for formulation. The determination of the particle size of the dried press cake led to an estimated mean particle size of 500 µm by sieving of the clumpy material.

Additional information

The test item is usually isolated by spray drying into the composite microgranular form or dedusting agent is added to form agglomerates of particles. As such, the particle size is not a function of the chemical but a function of the spray dryer and technique used; a typical particle size distribution for reactive dyes isolated as low dust granules is as follows:

10% < 123 µm; 25% < 159 µm; 50% < 207 µm; 75% < 266 µm; 90% < 326 µm

For testing purposes, the test material was isolated as wet press cake and dried. This led to a clumpy material that is usually further milled to allow proper testing of physico-chemical ant (eco)toxicological tests. The dried press cake was investigated for its particle size.

The test material is a clumpy powder; by visual observation, the particle size of the test item was too big to determine the distribution by laser diffraction method. Based on the visual observation, the sieve method was selected. Only 0.02 % (w/w) of the test item were below 75 μm. The approximate mean particle size was 500 µm.