Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-247-6 | CAS number: 5333-84-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Acute toxicity to Fish: 96 hour LC50 - >100mg/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
In a 96-hour acute toxicity study, Medaka (Oryzias latipes) were exposed to tetrahydromethylphthalic anhydride (MTHPA), of which 3 -THPA D4 is an isomer, at a nominal limit concentration of 100 mg/L under flow through conditions. The EC50 and NOEC values, based on mortality/sublethal effects, were> 100 and = 100 mg/L, respectively. Sublethal effects were not observed in the groups exposed to 100 mg/L of tetrahydromethylphthalic anhydride.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
