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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)
Version / remarks:
2013
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid
EC Number:
849-166-3
Cas Number:
83841-00-3
Molecular formula:
C4H5NO4
IUPAC Name:
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid
Test material form:
solid

Reagents

Reagent:
water

Results and discussion

pH value
Key result
pH value:
2.22
Temp.:
20 °C
Concentration:
1 other: % w/v

Any other information on results incl. tables

Table 1: Results of pH value measurements

Determination

pH value

Overall mean pH

After 1 minute

After 2 minutes

After 10 minutes

1

2.21

2.21

Not required

2.22

2

2.23

2.23

Not required

Applicant's summary and conclusion

Conclusions:
The pH value of a 1% w/v aqueous solution of the substance was determined to be 2.22 at 20 °C.
Executive summary:

The pH value of the substance was studied under GLP in accordance with OECD TG 122, using a calibrated pH meter. Two test solutions at a nominal concentration of 1% w/v were prepared by diluting aliquots of test substance (1.0275 and 1.0100 g) to 100 mL of high purity water (with a specification of resistance of >15 MΩ and a typical TOC content of 20 ppb). Each sample was then transferred to a sample cup and allowed to settle for a period of 1 minute before the pH value was determined. A second reading was done after 2 minutes. As the difference between the two readings did not exceed 0.1 pH units, a third reading after 10 minutes was not required. The results of the measurements were 2.21 and 2.23, giving a mean pH value of 2.22 at a concentration of 1% w/v and a temperature of 20 °C.