(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: UN Test O.1: “Test for Oxidizing Solids”

Version / remarks:

2015

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Contact with:

powdered cellulose

Duration of test (contact time):

>= 3 min

Key result

Sample tested:

4:1 sample-to-cellulose ratio

Parameter:

mean burning time

Result:

563 s

Key result

Sample tested:

1:1 sample-to-cellulose ratio

Parameter:

mean burning time

Result:

267 s

Key result

Sample tested:

reference: 3:7 mixture potassium bromate + cellulose

Parameter:

mean burning time

Result:

64 s

Applied power to the ignition coil was 150±7 W.

Table 1: Burning times

Test number	Burning times (s)
	Test substance mixed with cellulose		Reference substance mixed with cellulose
	4:1	1:1	3:7
1	330	287	58
2	385	270	46
3	660	418	75
4	660	220	78
5	780	142	61
Mean	563	267	64

The 4:1 mixture of test substance with cellulose smouldered initially before igniting and burning with a small flame. In each case, once the flames had extinguished the combustion was incomplete, although the mixtures did continue to fume. The 1:1 mixtures ignited and burned with a flame from the start of the test, although the combustion was incomplete in three of the five mixtures once the flames had extinguished.

Interpretation of results:

GHS criteria not met

Conclusions:

The mean burning times of the 4:1 and 1:1 mixtures of the test substance with cellulose were both much greater than the mean burning time 3:7 mixture of the reference potassium borate with cellulose. The substance is not considered to be an oxidising solid.

Executive summary:

The oxidising properties of the substance were studied under GLP in accordance with UN Test O.1.

The substance was ground and sieved to particle size equal to or less than 500 µm and mixed with dry fibrous cellulose in ratios of 1:1 and 4:1, by mass, of sample to cellulose. The burning characteristics of the mixtures were compared with a standard 3:7 reference mixture, by mass, of potassium bromate to cellulose. Each test mixture was formed into a conical pile of base diameter 70 mm, covering a looped ignition wire resting on a low heat conducting base plate. Electrical power was applied to the ignition wire until the end of the test because the mixtures showed signs of ignition. The 4:1 mixtures smouldered before igniting and burning with a small flame and continued to fume after the flames had extinguished following incomplete combustion; the 1:1 mixtures ignited and burned with a flame, but combustion was incomplete in three of five tested mixtures. The burning time was recorded from the initial application of power to the wire until the end of the main reaction. The mean burning time from five evaluations was as follows:

- 563 seconds for 4:1 mixtures (test substance:cellulose)

- 267 seconds for 1:1 mixtures (test substance:cellulose)

- 64 seconds for 3:7 mixtures (reference:cellulose)

The mean burning times of the mixtures of test substance with cellulose were much greater than those of the potassium borate/cellulose mixtures. In accordance with the criteria of UN Test O.1, the substance was not considered to be an oxidising solid.

Description of key information

Non-oxidising (GLP, UN Test O.1)

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Justification for classification or non-classification

The mean burning times of 4:1 and 1:1 mixtures of the substance with cellulose were much greater than the mean burning time of a 3:7 mixture of the reference substance potassium borate with cellulose. The substance does not meet the criteria of UN Test O.1 for an oxidising solid and therefore is not classified in accordance with CLP Regulation (EC) No. 1272/2008.