Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07 Feb 2019 to 19 Apr 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
GLP compliance:
yes
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
2,9,16,23-tetrakis(2,5-di-tert-butyl-4-methoxyphenoxy)phthalocyanine
EC Number:
831-167-5
Cas Number:
2126827-44-7
Molecular formula:
C92H106N8O8
IUPAC Name:
2,9,16,23-tetrakis(2,5-di-tert-butyl-4-methoxyphenoxy)phthalocyanine
Test material form:
solid
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 2715/18/01
- Expiration date of the lot/batch: 01 July 2020
- Purity test date: 11 July 2018

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature protected from light
- Stability under test conditions: Stable

Results and discussion

Water solubility
Key result
Water solubility:
< 1 µg/L
Temp.:
20 °C
pH:
7.4

Applicant's summary and conclusion

Conclusions:
The water solubility of the substance is <1µg/L.
Executive summary:

The water solubility of the substance has been determined by UPLC-MS according to OECD guideline 105, EC guideline A.6, and OPPTS 830.7840, and GLP standards.

The UPLC-MS method has been validated within the study report and found to be an acceptable method for water solublity determination.

The water solubility of the substance is <1µg/L at 20°C and a pH of 7.4.