1H-Isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes

Type of method:

effusion method: vapour pressure balance

Test material

Test material information

Constituent 1

Reference substance name:

2-({(5S)-2-Oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione

EC Number:

610-201-0

Cas Number:

446292-08-6

Molecular formula:

C22 H19 N3 O6

IUPAC Name:

2-({(5S)-2-Oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione

Results and discussion

Vapour pressure

Vapour pressure 1

Key result

Temp.:

20 °C

Vapour pressure:

< 0 hPa

Vapour pressure 2

Temp.:

25 °C

Vapour pressure:

< 0 hPa

Vapour pressure 3

Temp.:

50 °C

Vapour pressure:

< 0 hPa

Vapour pressure 4

Temp.:

196.08 °C

Vapour pressure:

0 hPa

Vapour pressure 5

Temp.:

218.02 °C

Vapour pressure:

0 hPa

Any other information on results incl. tables

The mean deviation between measured and calculated values below the melting temperature is 28,6%.

The given data points have been obtained by calculation using the Antoine equation.

Applicant's summary and conclusion

Conclusions:

Results of regression calculation of Oxaphthalimid : 20 °C: < 1.00E-05 hPa; 25°C:< 1.00E-05 hPa; 50 °C:<1.00 E-05 hPa; 196.08 °C: 4.50 E-06 hPa; 218.02°C: 1.29 E-04hPa