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EC number: 700-867-1 | CAS number: -
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient documentation for an assessment of reliability.
- GLP compliance:
- not specified
- Medium:
- methanol
- Solubility:
- 13 g/L
- Temp.:
- 20 °C
- Medium:
- ethanol
- Solubility:
- 1.5 g/L
- Temp.:
- 20 °C
- Medium:
- isopropanol
- Solubility:
- 0.2 g/L
- Temp.:
- 20 °C
- Medium:
- other: dichloromethane
- Solubility:
- 0.02 g/L
- Temp.:
- 20 °C
- Medium:
- other: 2-propanone
- Solubility:
- 0.07 g/L
- Temp.:
- 20 °C
- Medium:
- ethyl acetate
- Solubility:
- < 0.01 g/L
- Temp.:
- 20 °C
- Medium:
- other: methylbenzene
- Solubility:
- 0.03 g/L
- Temp.:
- 20 °C
- Medium:
- other: 4-methyl-2-pentanone
- Solubility:
- 0.01 g/L
- Temp.:
- 20 °C
- Medium:
- other: 2-butanone
- Solubility:
- 0.17 g/L
- Temp.:
- 20 °C
- Details on results:
- no data
- Conclusions:
- The solubility of T002102 was determined in different organic solvents, ranging from <0.01 g/L in ethyl acetate to 13 g/L in methanol (at 20°C).
Reference
Table 1 Solubility of the T002102 at 20 deg C
| Solvent | Concentration in g/ mL solution |
| 1 -methoxy-2-propanol | 0.15 |
| N,N-dimethylacetamide | 12 |
| acetic acid | 4 |
| Tetrahydrofuran | < 0.01 |
| N,N-dimethylformamide | 16 |
Description of key information
A K4 study (J&J PRD) reports various solubilities of test substance in different organic solvents.
Key value for chemical safety assessment
Additional information
| solvent | solubility g/L (20°C) |
| methanol | 13 |
| ethanol | 1,5 |
| 2-propanol | 0,2 |
| dichloromethane | 0,02 |
| 2-propanone | 0,07 |
| ethyl acetate | < 0,010 |
| methylbenzene | 0,03 |
| 4-methyl-2-pentanone | 0,01 |
| 2-butanone | 0,17 |
| 1-methoxy-2-propanol | 0,15 |
| N,N-dimethylacetamide | 12 |
| acetic acid | 4 |
| THF | < 0,010 |
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