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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

toxicity to aquatic algae and cyanobacteria
Type of information:
Adequacy of study:
other information
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification

Data source

Reference Type:
other: QSAR-tool
Estimation Program Interface EPI Suite (TM) v4.11: ECOSAR v1.11
United States Environmental Protection Agency, Washington, DC, USA.
Bibliographic source:

Materials and methods

Principles of method if other than guideline:
ECOSAR™ Version 1.11 (Sept 2012): The Ecological Structure Activity Relationships (ECOSAR) Class Program estimates the aquatic toxicity of industrial chemicals. The program estimates acute (short-term) toxicity and chronic (long-term or delayed) toxicity to aquatic organisms to fish, aquatic invertebrates and green algae.
GLP compliance:

Results and discussion

Effect concentrations
Key result
96 h
Dose descriptor:
Effect conc.:
0.23 mg/L

Any other information on results incl. tables

ECOSAR Program (v1.11) Results:


ECOSAR Version 1.11 Results Page



CAS Num:


MOL FOR: C10 H21 CL1

MOL WT : 176.73

Log Kow: 5.506     (EPISuite Kowwin v1.68 Estimate)

Log Kow:           (User Entered)

Log Kow:           (PhysProp DB exp value - for comparison only)

Melt Pt:           (User Entered for Wat Sol estimate)

Melt Pt: -31.30    (deg C, PhysProp DB exp value for Wat Sol est)

Wat Sol: 1.257     (mg/L, EPISuite WSKowwin v1.43 Estimate)

Wat Sol:           (User Entered)

Wat Sol:           (PhysProp DB exp value)




Values used to Generate ECOSAR Profile


Log Kow: 5.506     (EPISuite Kowwin v1.68 Estimate)

Wat Sol: 1.257     (mg/L, EPISuite WSKowwin v1.43 Estimate)




ECOSAR v1.11 Class-specific Estimations


Neutral Organics


ECOSAR Class                Organism           Duration End Pt  mg/L (ppm)

=========================== ================== ======== ======  ==========

Neutral Organics          : Fish               96-hr    LC50       0.103

Neutral Organics          : Daphnid            48-hr    LC50       0.081

Neutral Organics          : Green Algae        96-hr    EC50       0.230

Neutral Organics          : Fish                         ChV        0.015

Neutral Organics          : Daphnid                      ChV        0.019

Neutral Organics          : Green Algae                  ChV        0.124

Neutral Organics          : Fish (SW)          96-hr    LC50       0.132

Neutral Organics          : Mysid              96-hr    LC50       0.009

Neutral Organics          : Fish (SW)                    ChV        0.122

Neutral Organics          : Mysid (SW)                   ChV      0.00028

Neutral Organics          : Earthworm          14-day   LC50     133.015 *


Note: * = asterisk designates: Chemical may not be soluble enough to

measure this predicted effect. If the effect level exceeds the

water solubility by 10X, typically no effects at saturation (NES)

are reported.



Class Specific LogKow Cut-Offs


If the log Kow of the chemical is greater than the endpoint specific cut-offs

presented below, then no effects at saturation are expected for those endpoints.


Neutral Organics:


Maximum LogKow: 5.0 (Fish 96-hr LC50; Daphnid LC50, Mysid LC50)

Maximum LogKow: 6.0 (Earthworm LC50)

Maximum LogKow: 6.4 (Green Algae EC50)

Maximum LogKow: 8.0 (ChV)

Applicant's summary and conclusion