Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Not irritating or sensitising in human volunteers

Additional information

There is ample data in numerous studies to demonstrate that triethyl citrate (TEC) is not a skin irritant or sensitiser in humans. This is in contrast to the strong sensitisation reaction of TEC in the guinea pig maximisation assay (GPMT). As another larger ester, ATBC, was negative in the GPMT it is reasoned that the target substance, ATHC, is not a dermal sensitiser.