2,7-Naphthalenedisulfonic acid, 5-(acetylamino)-3-[2-[5-[[4-chloro-6-[[3-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]diazenyl]-4-hydroxy-, sodium salt (1:4)

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 30 July 2018 to 21 November 2018

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

GLP compliance:

yes

Type of method:

Laser scattering/diffraction

Type of distribution:

volumetric distribution

Mass median aerodynamic diameter:

53.9 µm

Percentile:

D50

Mean:

ca. 53.9 µm

St. dev.:

1.12

No.:

#1

Size:

> 0 - <= 50 µm

Distribution:

55.42 %

No.:

#2

Size:

> 50 - <= 100 µm

Distribution:

39.85 %

No.:

#3

Size:

> 100 µm

Distribution:

4.73 %

Table 1. Particle Size Distribution of CR SR94

	Replicate 1	Replicate 2	Replicate 3
Particle size distribution (µm)	54.6	53.4	53.9
Mean Particle size distribution (µm)	53.9
RSD (%)	1.12%

Conclusions:

The mass median diameter is 53.9 μm.

Executive summary:

The determination of the Particle Size Distribution of CR SR94 was performed in accordance with OECD Guideline no. 110.

The method can only be applied to water-insoluble (<10^-6 g/L), powdered type products.

The Particle Size Distribution of CR SR94 was determined to be 53.9 μm.

Description of key information

The mass median diameter is 53.9 μm.