(6-Bromo-2-pyridinyl)(4-methylphenyl)methanone

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental start date 14 September 2018, Experimental completion date 09 November 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Test material

Test material information

1

Reference substance name:

2-bromo-6-(4-methylbenzoyl)pyridine

EC Number:

618-079-0

Cas Number:

87848-95-1

Molecular formula:

C13H10BrNO

IUPAC Name:

2-bromo-6-(4-methylbenzoyl)pyridine

Results and discussion

Boiling point

Key result

Atm. press.:

1 031 mBar

Decomposition:

yes

Decomp. temp.:

ca. 250 °C

Any other information on results incl. tables

As the boiling tube was heated, gradual darkening was observed at elevated temperature, but no boiling below 360˚C. As it was difficult to ascertain the onset of this apparent decomposition, DSC was also employed to further investigate.

The DSC trace showed gradual deviation from the baseline from approximately 250°C, with a significant exotherm noted at approximately 300˚C. The observations were consistent with decomposition of the test item. A dark brown residue was present in the crucible at the end of the test.

Applicant's summary and conclusion

Conclusions:

The boiling temperature of 2-Bromo-6-(4-toluoyl)pyridine was not determinable as the test item decomposed at temperatures above approximately 250°C without boiling.