Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

A study according to OECD 209 was performed to assess the inhibitory effect of IFF FRET 11 -0078 on the respiration of activated sewage sludge.

Cultures of activated sewage sludge were incubated with synthetic sewage under vigorous aeration and in the presence of the test substance.

Aeration was interrupted after 3 hours and the rates of respiration measured electrochemically for each culture.

The percentage inhibition of respiration was calculated for each culture after the contact period by comparing oxygen depletion rates for the test substance with those for the negative control culture. A positive control i.e. 3,5-dichlorophenol was tested concurrently with the test substance in order to demonstrate the satisfactory performance of the procedure.

The EC50 (respiration inhibition) values for the substance was 410 mg/l for the 3-hour contact time, with 95% confidence limits 380 to 440 mg/L. 

Key value for chemical safety assessment

EC50 for microorganisms:
410 mg/L

Additional information