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Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
(2E,2'E)-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diylbis(2-methylpropane-2,1-diyl) bis(2-cyano-3-(3,4-dimethoxyphenyl)acrylate)
Cas Number:
2233585-18-5
Molecular formula:
C39H46N2O12
IUPAC Name:
(2E,2'E)-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diylbis(2-methylpropane-2,1-diyl) bis(2-cyano-3-(3,4-dimethoxyphenyl)acrylate)
Test material form:
solid
Remarks:
Light yellow solid (powder)

Results and discussion

Water solubility
Water solubility:
< 0.025 mg/L
Incubation duration:
ca. 5 d
Temp.:
20 °C
pH:
ca. 5.8

Applicant's summary and conclusion

Conclusions:
Within the test conditions, column elution method was used at high flow rate (25mL/h) and low flow rate (12.5mL/h) to conduct the water solubility test. The results showed that all the concentrations of the five consecutive samples were less than the limit of detection. As the limit of detection of the analysis method was 0.0248 mg/L, so the water solubility of test substance was below 2.48×10-5 g/L.