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EC number: 824-458-3 | CAS number: 1263679-68-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29/11/2016 - 17/02/2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (1Z)-1-chloro-2,3,3-trifluoroprop-1-ene
- EC Number:
- 824-458-3
- Cas Number:
- 1263679-68-0
- Molecular formula:
- C3H2ClF3
- IUPAC Name:
- (1Z)-1-chloro-2,3,3-trifluoroprop-1-ene
- Test material form:
- liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
- Details on test solutions:
- The test solutions were prepared according to the methods described in Appendix 3. Test solutions, approximately 100 mL, were poured into each of the five vessels per test group and immediately plugged with a ground-in stopper to prevent volatilization of the test substance. The volumes of the test solution in the vessels were adjusted to 100 mL by plugging. One of five vessels of each test group was used for measuring the test conditions.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Scientific name: Daphnia magna
Source: National Institute for Environmental Studies, Japan
Date of receipt: July 18, 1995 (The daphnids have been maintained at the testing facility).
Sensitivity to the reference substance: Acute immobilisation tests of the reference substance (potassium dichromate, guaranteed reagent) have been conducted periodically (approximately every 6 months).
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 228 mg CaC03/L
- Test temperature:
- 20±1 °C
- pH:
- 8.3
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 39.7 mg/L
- Nominal / measured:
- meas. (initial)
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 10.8 mg/L
- Nominal / measured:
- meas. (initial)
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 123 mg/L
- Nominal / measured:
- meas. (initial)
- Basis for effect:
- mobility
- Details on results:
- In the control, the percentage of immobilisation was 0% at the end of exposure, and no daphnids were observed floating on the surface of the water.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- An acute immobilisation test of the test substance with Daphnia magna was conducted in order to determine the median effect concentration (EC50) of the test substance for 48-hour exposure period. The 48-hour median effect concentration (EC50) was 39.7 mg/L (95% confidence limits: 33.5-47.6 mg/L).
- Executive summary:
An acute immobilisation test of the test substance with Daphnia magna was conducted in order to determine the median effect concentration (EC50) of the test substance for 48-hour exposure period. The 48-hour median effect concentration (EC50) was 39.7 mg/L (95% confidence limits: 33.5-47.6 mg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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