Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
BG Chemie - Potential Health Hazards of Existing Chemiclas (TOXIKOLOGISCHE BEWERTUNG zu Benzolsulfonsäurehydrazid, BG-Nr. 220)
Author:
Berufsgenossenschaft Rohstoffe und chemische Industrie (BG RCI)

Materials and methods

GLP compliance:
not specified

Test animals

Species:
rabbit
Strain:
New Zealand White
Remarks:
male and female (3-4 kg)

Test system

Type of coverage:
other: using an adhesive dressing
Observation period:
7 days

Results and discussion

Any other information on results incl. tables

The treatment produced no skin changes of any kind.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Benzene sulphonic acid hydrazide was assessed as non-irritant (irritant value 0).