C10-C16-(linear and branched)-alkyl esters of salicylic acid.

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Justification for type of information:

The aquatic toxicity of the substance is unlikely to occur because the substance is highly insoluble in water.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

water solubility

Type of information:

other: estimated from EPISUITE WSKOW (v1.42).

Adequacy of study:

key study

Study period:

2018-2019

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification

Reason / purpose for cross-reference:

reference to other study

Remarks:

water solubility calculated from experimental value of logKow

Qualifier:

no guideline required

Principles of method if other than guideline:

EPISUITE WSKOW (v1.42).

Type of method:

other: QSAR ELABORATION

Key result

Water solubility:

ca. 0.094 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Octyl Salicylate

Key result

Water solubility:

ca. 0.079 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Nonyl Salicylate

Key result

Water solubility:

ca. 0.065 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Decyl Salicylate

Key result

Water solubility:

ca. 0.065 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Isodecyl Salicylate

Key result

Water solubility:

ca. 0.054 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Undecyl Salicylate

Key result

Water solubility:

ca. 0.045 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Dodecyl Salicylate

Key result

Water solubility:

ca. 0.037 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Tridecyl Salicylate

Key result

Water solubility:

ca. 0.037 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Isotridecyl Salicylate

Key result

Water solubility:

ca. 0.031 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Tetradecyl Salicylate

Key result

Water solubility:

ca. 0.021 mg/L

Temp.:

25 °C

pH:

> 6 - < 8

Remarks on result:

not measured/tested

Remarks:

QSAR from Hexadecyl Salycilate

Conclusions:

the water solubility range is between 0.02079 and 0.0942 mg/L.