Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14 January 2014 to 16 January 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised with its purity. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry
Specific details on test material used for the study:
- Storage condition of test material: In refrigerator (2-8°C) protected from light, container flushed with nitrogen
- Stability at higher temperatures: Yes, maximum temperature: 40°C, maximum duration: 10 days
Temp.:
20 °C
Vapour pressure:
5.8 Pa
Key result
Temp.:
25 °C
Vapour pressure:
11 Pa
Key result
Transition / decomposition:
no

Table 4.6/1: Results of the isothermal TGA analysis

 

Temperature [°C]

Weight loss [μg/min]

νT [g/cm2/h] 

log νT 

log PT 

PT [Pa]

25

6.451

7.70 x 10-4

-3.11

1.01

10

7.276

8.69 x 10-4

-3.06

1.07

12

30

12.25

1.46 x 10-3

-2.83

1.33

22

12.64

1.51 x 10-3

-2.82

1.35

22

35

20.70

2.47 x 10-3

-2.61

1.60

40

21.13

2.52 x 10-3

-2.60

1.61

41

40

32.79

3.91 x 10-3

-2.41

1.83

68

33.98

4.06 x 10-3

-2.39

1.85

71

 

Table 4.6/2: Vapour pressure of the test substance

 

Temperature [°C]

log PT

PT [Pa]

PT [mmHg]

20

0.76

5.8

4.3 x 10-2

25

1.05

11

8.4 x 10-2

The equation of the curve was: log PT = -5012 × 1/T + 17.86 (r = 0.997, n = 8).

Conclusions:
Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
Executive summary:

The vapour pressure of the test substance was measured, under GLP, according to OECD 104 / EU A4 guideline, using the isothermal thermogravimetric effusion method.

The system was calibrated with five reference substances, with VP between 1.33 E-8 and 2.34 E+3 Pa at 20°C, as a linear regression.

Isothermal TGA analysis of the test substance was performed between 25 °C and 40 °C. The vapour pressure of the test substance at 20°C and 25°C were determined using the vapour pressure regression curve.

The vapour pressure of the test substance at 20 °C (293 K) and 25 °C (298 K) was 5.8 Pa (4.3 × 10-2 mm Hg) and 11 Pa (8.4× 10-2 mm Hg), respectively.

Description of key information

Low volatility.

Key value for chemical safety assessment

Vapour pressure:
11 Pa
at the temperature of:
25 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study. The interpolated result at 25°C is retained as key value.