Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-372-6 | CAS number: 98730-04-2
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
A study of bioaccumulation in a freshwater system is available for benoxacor using fathead minnow (Pimephales promelas). The study was performed according to a Springborn protocol with modifications from Fish Bioconcentration Toxicity Test Environmental Effects Test guidelines (EPA, 1982) and provides an equilibrium bioconcentration factor of 94.
Key value for chemical safety assessment
- BCF (aquatic species):
- 94 dimensionless
Additional information
The key study (Suprenant, 1986) investigated the potential for bioaccumulation of benoxacor in aquatic systems. The test organism was fathead minnow (Pimephales promelas) and the study was conducted to a Springborn protocol including procedures from Macek et al, 1975 and Barrows et al, 1980 with modifications from Fish Bioconcentration Toxicity Test Environmental Effects Test guidelines (EPA, 1982). The study was GLP compliant and is considered to be reliable without restriction (Klimisch 1).
During the exposure time of 9 days fathead minnows were continuously exposed to a nominal concentration of 0.12 mg/L of carbon-14-labelled benoxacor in well water. Thereafter, all remaining fish were transferred to flowing, untreated dilution water for a 42-day depuration time. A mean water concentration of 0.12 mg benoxacor/L was measured during the 9 day exposure period.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
